Abstract Library

#2884 An Infectious Diseases Specialist NET Patient Looks at Management of NETs

Introduction: Medical specialties may develop practices minimally influenced by other specialties.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Schmid G,

Keywords: neuroendocrine, everolimus, somatostatin analogue, drug levels,

#2846 Whole Genome DNA Methylation Profiling Identifies Neuroendocrine Tumor Origin

Introduction: Determining the origin of a neuroendocrine tumor (NET) of unknown primary can be challenging. Liver metastases can originate from any organ in the body, while pulmonary NETs can be metastases but also primary tumors. This especially holds true for Multiple Endocrine Neoplasia Type 1 patients, who often have multiple primary pancreatic and intestinal NETs. It is important to know the origin of the primary tumor since resection or ablation is crucial in case of treatment with curative intent. Furthermore, the site of origin determines prognosis, treatment options and eligibility for clinical trials.

Conference: 17th Annual ENETSConcerence (2020)

Presenting Author:

Authors: Hackeng W, Geisenberger C, de Leng W, Morsink F, Vriens M,

Keywords: Methylation profiling, Neuroendocrine tumor, Machine Learning, Unknown Primary,

#1585 Incidence and Characteristics of Ileo-colonic Neuroendocrine Tumours Identified in the UK Bowel Cancer Screening Programme

Introduction: Colorectal cancer is the third most common cancer in the UK this had led to development of the bowel cancer screening programmes (BCSPs).There are few epidemiological data on rectal or ileal NETs diagnosed in BCSPs.

Conference: 14th Annual ENETSConcerence (2017)

Presenting Author: Srirajaskanthan R

Authors: Basuroy R, O'Donnell K, Brooks C, Srirajaskanthan R, Ramage J,

Keywords: screening,

#1483 Biomarker and Target Identification in GEP-NET: From in Silico Prediction to Validation on Patient Tissues

Introduction: Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are a heterogeneous group of tumors. Somatostatin agonist treatment has a key role in the management of GEP-NET. However, the prognosis of these tumors varies between individuals. There is, therefore, a need to identify novel prognostic and predictive biomarkers of therapeutic efficacy, as well as to propose novel therapeutic strategies.

Conference: 13th Annual ENETSConcerence (2016)

Presenting Author:

Authors: Tourlet S, Gentien D, Bauchet A, Nicolas A, Blachon J,

Keywords: GPCR, miR,

#1246 68 Yr Female with a Growing Inoperable Myocardial Metastase

Introduction: Two recent studies shows that cardiac metastases occur rather frequently, 13% in a population of serotoninproducing NETs(Noordzij 2014) and 4% in our own patient kohort of ileal NETs(Calissendorff 2014).

Conference: 12th Annual ENETSConcerence (2015)

Presenting Author: Ekberg K

Authors: Linder Ekberg K,

Keywords: Myocardiac heart metastase, NET, ileal NET,